Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Choline (from 630 mg Choline Bitartrate)
250 mg
45%
Inositol
250 mg
â€
Top Medical Research Studies
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Read More
Most Useful Reviews
9
Calm heart rate
14 people found this helpful
Cospa is fantastic. I found that the frustrating hurdles were diminishing year by year, prompting me to try it. I was astonished at its effectiveness for such a low-cost supplement; it made my heart markedly calmer. Initially, I thought I was entering menopause due to my age, but this was more effective than any other products I'd tried.
Read More
6
Enhances brain capacity
1 people found this helpful
Great for improving brain capacity. Choline and Inositol act on the Central Nervous System, enhancing brain function and communication. Choline uniquely moves fats from the liver to be converted into energy. It complements carnitine in fat metabolism and manages homocysteine to maintain energy production. Choline is essential for the body’s normal functioning and is particularly important for the liver, heart, and brain development.
Read More
9
Heart protection
This product effectively promotes heart protection and supports mitochondria health. It's reasonably priced and works well.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Calm heart rate
14 people found this helpful
Cospa is fantastic. I found that the frustrating hurdles were diminishing year by year, prompting me to try it. I was astonished at its effectiveness for such a low-cost supplement; it made my heart markedly calmer. Initially, I thought I was entering menopause due to my age, but this was more effective than any other products I'd tried.
Read More
6
Enhances brain capacity
1 people found this helpful
Great for improving brain capacity. Choline and Inositol act on the Central Nervous System, enhancing brain function and communication. Choline uniquely moves fats from the liver to be converted into energy. It complements carnitine in fat metabolism and manages homocysteine to maintain energy production. Choline is essential for the body’s normal functioning and is particularly important for the liver, heart, and brain development.
Read More
9
Heart protection
This product effectively promotes heart protection and supports mitochondria health. It's reasonably priced and works well.
Read More
0
Unsuitable supplement
2 people found this helpful
I initially felt very energetic, but then experienced heart palpitations and headaches. Upon stopping all supplements, I discovered they were the cause. They did not significantly reduce visceral fat and affected my body, leading me to discard the two cans I had purchased.
Read More
5
Stable spirit
10 people found this helpful
I've taken this product three times now. Initially, I did not feel much effect on an empty stomach. The second combination led to irritation, but the third time with potassium calcium post-meal calmed my heart and made me comfortable. The effect seemed consistent throughout that day, which encouraged me to consider my combinations more carefully.
Read More
Frequently Asked Questions
9
Calm heart rate
14 people found this helpful
Cospa is fantastic. I found that the frustrating hurdles were diminishing year by year, prompting me to try it. I was astonished at its effectiveness for such a low-cost supplement; it made my heart markedly calmer. Initially, I thought I was entering menopause due to my age, but this was more effective than any other products I'd tried.
7.5
Minimal issues
6 people found this helpful
I observed no significant negatives apart from slight heartburn when taken on an empty stomach. My physical condition showed no decline, and while the supplement only partially achieved its intended purpose, it may be clearer with time as I aim to prevent heart diseases.
5
Stable spirit
10 people found this helpful
I've taken this product three times now. Initially, I did not feel much effect on an empty stomach. The second combination led to irritation, but the third time with potassium calcium post-meal calmed my heart and made me comfortable. The effect seemed consistent throughout that day, which encouraged me to consider my combinations more carefully.
9
Heart protection
This product effectively promotes heart protection and supports mitochondria health. It's reasonably priced and works well.
7.5
Calming effects
1 people found this helpful
I began taking this to achieve mental stability as I occasionally experience panic attacks. I feel slightly calmer and more energetic, so I intend to continue using it.
5
Less hair loss
10 people found this helpful
I initially bought this for panic attacks. I don’t think it made much difference for that, but I’ve noticed less hair loss — I’m experiencing male pattern balding despite being female — and my hair has improved. It's notably reduced my hair fall rate. This is my second bottle, and I have no plans to stop taking it.
0
Unsuitable supplement
2 people found this helpful
I initially felt very energetic, but then experienced heart palpitations and headaches. Upon stopping all supplements, I discovered they were the cause. They did not significantly reduce visceral fat and affected my body, leading me to discard the two cans I had purchased.
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
References
- Oknińska M, El-Hafny-Rahbi B, Paterek A, Mackiewicz U, Crola-Da Silva C, et al. Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells. J Cell Mol Med. 2020;24:2272. 10.1111/jcmm.14909
